About the Project
Wastewater-based epidemiology (WBE) has proven utility for tracking the emergence and spread of pathogenic microbial species. Metagenomics is commonly used to profile whole microbial communities, as well as individual antimicrobial resistance genes (ARGs). However, these data tend to offer relatively course resolution at the intra-species level, and there can be considerable technical challenges in assembling plasmid sequences.
This project will focus on high-resolution localised surveillance of key target pathogenic strains exhibiting antimicrobial resistance (AMR) in wastewater. We will develop an extensive suite of bespoke markers targeting high priority E. coli and Klebsiella strains, and their plasmids, known to be circulating within communities local to Bath. We will use high throughput qPCR to track strain dynamics across the three sites over time, thus providing early warning of the emergence of high-risk pathogens.
Candidate Requirements:
Applicants should hold, or expect to receive, a First Class or high Upper Second Class UK Honours degree (or the equivalent) in a relevant subject. A master’s level qualification would also be advantageous. Non-UK applicants must meet the programme’s English language requirement by the application deadline.
Enquiries and Applications:
Informal enquiries are encouraged and should be directed to Prof Edward Feil (bssef@bath.ac.uk).
Formal applications should be submitted via the University of Bath’s online application form for a PhD in Biology prior to the closing date of this advert.
Equality, Diversity and Inclusion:
We value a diverse research environment and aim to be an inclusive university, where difference is celebrated and respected. We welcome and encourage applications from under-represented groups.
If you have circumstances that you feel we should be aware of that have affected your educational attainment, then please feel free to tell us about it in your application form. The best way to do this is a short paragraph at the end of your personal statement.
Funding Notes
Candidates may be considered for a University of Bath studentship tenable for 3.5 years. Funding covers tuition fees, a stipend (£21,805 p/a in 2026/7) and access to a training support budget.
